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Cellosaurus PAX-C002 (CVCL_D7E6)

[Text version]
Cell line name PAX-C002
Synonyms PAXC002
Accession CVCL_D7E6
Resource Identification Initiative To cite this cell line use: PAX-C002 (RRID:CVCL_D7E6)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C201010.
Population: Chinese.
Characteristics: Established from a xenograft produced by subcutaneous injection of tumor cells into SCID mice (PubMed=22076649).
Characteristics: Gemcitabine resistant (Patent=CN102329775B; PubMed=22076649).
Doubling time: 47.65 hours (Patent=CN102329775B); ~48 hours (PubMed=22076649).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): PubMed=22325559

Markers:
AmelogeninX
CSF1PO12
D5S81812
D7S8208,9
D13S31711,12
D16S5399
TH017,9
TPOX8,11
vWA16,18

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Publications

PubMed=22076649; DOI=10.3892/ijo.2011.1254
Hu G., Li F., Ouyang K.-D., Xie F.-B., Tang X.-Z., Wang K., Han S.-F., Jiang Z.-Z., Zhu M.-H., Wen D.-Y., Qin X.-R., Zhang L.-Y.
Intrinsic gemcitabine resistance in a novel pancreatic cancer cell line is associated with cancer stem cell-like phenotype.
Int. J. Oncol. 40:798-806(2012)

PubMed=22325559; DOI=10.1111/j.1742-4658.2012.08521.x
Li F., Hu G., Jiang Z.-Z., Guo J., Wang K., Ouyang K.-D., Wen D.-Y., Zhu M.-H., Liang J.-X., Qin X.-R., Zhang L.-Y.
Identification of NME5 as a contributor to innate resistance to gemcitabine in pancreatic cancer cells.
FEBS J. 279:1261-1273(2012)

Patent=CN102329775B
Qin X.-R., Zhu M.-H., Hu G., Xie F.-B., Tang X.-Z., Wen D.-Y.
Gemcitabine-tolerant human pancreatic cancer cell line and application thereof.
Patent number CN102329775B, 19-Aug-2015

Cross-references
Cell line databases/resources CCRID; 4201PAT-CCTCC00330
Experimental variables resources EFO; EFO_0022552
Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1