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Cellosaurus Leeporter MCF7 Nrf2 luciferase (CVCL_D7AT)

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Cell line name Leeporter MCF7 Nrf2 luciferase
Synonyms Nrf2 Leeporter Luciferase Reporter-MCF7
Accession CVCL_D7AT
Resource Identification Initiative To cite this cell line use: Leeporter MCF7 Nrf2 luciferase (RRID:CVCL_D7AT)
Comments Population: Caucasian.
Characteristics: Expresses Renilla luciferase under the transcriptional control of the antioxidant response element (ARE) (Abeomics=14-117ACL).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P27652; Renilla reniformis renilla-type luciferase.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Abeomics; 14-117ACL
Entry history
Entry creation10-Sep-2024
Last entry update14-Aug-2025
Version number3