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Cellosaurus M263 (CVCL_D759)

[Text version]
Cell line name M263
Accession CVCL_D759
Resource Identification Initiative To cite this cell line use: M263 (RRID:CVCL_D759)
Comments Part of: MD Anderson Cell Lines Project.
Doubling time: 23.3 hours (PubMed=20406486).
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Transcriptomics; RNAseq.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Web pages Info; MCLP; -; https://tcpaportal.org/mclp/
Publications

PubMed=20406486; DOI=10.1186/1479-5876-8-39; PMCID=PMC2876068
Jonas Norskov Sondergaard, Ramin Nazarian, Qi Wang, De-Liang Guo, Teli Hsueh, Stephen Mok, Hooman Sazegar, Laura E. MacConaill, Jordi Ginesta Barretina, Sarah M. Kehoe, Narsis Attar ...Show all 19 authors... , Erika Maria von Euw, Jonathan E. Zuckerman, Bartosz Chmielowski, Begonya Comin-Anduix, Richard C. Koya, Paul Salomon Mischel, Roger S. Lo, Antoni Ribas; Show fewer authors
Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.
J. Transl. Med. 8:39.1-39.11(2010)

PubMed=20689758; DOI=10.1593/neo.10414; PMCID=PMC2915408
William Douglas Tap, Ke-Wei Gong, Judy Dering, Yiou Tseng, Charles Ginther, Giovanni Pauletti, John A. Glaspy, Richard Essner, Gideon Bollag, Peter Hirth, Chao Zhang, Dennis Joseph Slamon;
Pharmacodynamic characterization of the efficacy signals due to selective BRAF inhibition with PLX4032 in malignant melanoma.
Neoplasia 12:637-649(2010)

PubMed=22194965; DOI=10.1371/journal.pone.0028973; PMCID=PMC3237573
Mohammad Atefi, Erika Maria von Euw, Narsis Attar, Charles Ng, Connie Chu, De-Liang Guo, Ramin Nazarian, Bartosz Chmielowski, John A. Glaspy, Begonya Comin-Anduix, Paul Salomon Mischel ...Show all 13 authors... , Roger S. Lo, Antoni Ribas; Show fewer authors
Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway.
PLoS ONE 6:e28973.1-e28973.12(2011)

PubMed=22515704; DOI=10.1186/1476-4598-11-22; PMCID=PMC3444881
Erika Maria von Euw, Mohammad Atefi, Narsis Attar, Connie Chu, Sybil Zachariah, Barry L. Burgess, Stephen Mok, Charles Ng, Deborah J.L. Wong, Bartosz Chmielowski, David I. Lichter ...Show all 15 authors... , Richard C. Koya, Tara A. McCannel, Elena Izmailova, Antoni Ribas; Show fewer authors
Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell lines.
Mol. Cancer 11:22.1-22.9(2012)

PubMed=24735930; DOI=10.1186/1476-4598-13-83; PMCID=PMC4021505
Amanda Lassen, Mohammad Atefi, Lidia Robert, Deborah J.L. Wong, Michael Cerniglia, Begonya Comin-Anduix, Antoni Ribas;
Effects of AKT inhibitor therapy in response and resistance to BRAF inhibition in melanoma.
Mol. Cancer 13:83.1-83.14(2014)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29229836; DOI=10.1073/pnas.1712064115; PMCID=PMC5748184
Ya-Peng Su, Wei Wei, Lidia Robert, Min Xue, Jennifer Tsoi, Angel Garcia-Diaz, Blanca Homet Moreno, Jungwoo Kim, Rachel Hin-Ying Ng, Jihoon W. Lee, Richard C. Koya ...Show all 15 authors... , Begonya Comin-Anduix, Thomas G. Graeber, Antoni Ribas, James Richard Heath; Show fewer authors
Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
Proc. Natl. Acad. Sci. U.S.A. 114:13679-13684(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D759
Encyclopedic resources Wikidata; Q54903574
Gene expression databases ArrayExpress; E-MTAB-5493
Polymorphism and mutation databases Cosmic; 1425348
Cosmic; 1459658
Cosmic; 1665017
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number16