Cellosaurus cell line HyCyte Daudi KO-hCMTM6 (CVCL

Cross-references
Cell line name	HyCyte Daudi KO-hCMTM6
Synonyms	hCMTM6 knockout Daudi
Accession	CVCL_D6B2
Resource Identification Initiative	To cite this cell line use: HyCyte Daudi KO-hCMTM6 (RRID:CVCL_D6B2)
Comments	Population: African; Kenyan. Doubling time: 24-48 hours (Hysigen=CGKO-M2520). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:19177; CMTM6. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: B-cell; CL=CL_0000236.
Sequence variations	Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line). Mutation; HGNC; HGNC:914; B2M; Simple; p.Met1Ile (c.3G>C); Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ala5_Ala80del (c.14_241del228); Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly266Glu (c.797G>A); ClinVar=VCV000161516; Zygosity=Heterozygous (from parent cell line).
Disease	EBV-related Burkitt lymphoma (NCIt: C27694) Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0008 (Daudi)
Sex of cell	Male
Age at sampling	16Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGKO-M2520
Encyclopedic resources	Wikidata; Q127382002
Entry history
Entry creation	02-May-2024
Last entry update	19-Dec-2024
Version number	3