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Cellosaurus RzM6-LC (CVCL_D637)

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Cell line name RzM6-LC
Accession CVCL_D637
Resource Identification Initiative To cite this cell line use: RzM6-LC (RRID:CVCL_D637)
Comments Population: Caucasian.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D636 (RzM6)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=19861417; DOI=10.1074/jbc.M109.043232; PMCID=PMC2794760
Tomohiro Nishimura, Michinori Kohara, Kosuke Izumi, Yuri Kasama, Yuichi Hirata, Ying Huang, Masahiro Shuda, Chise Mukaidani, Takashi Takano, Yuko Tokunaga, Hideko Nuriya ...Show all 15 authors... , Masaaki Satoh, Makoto Saito, Chieko Kai, Kyoko Tsukiyama-Kohara; Show fewer authors
Hepatitis C virus impairs p53 via persistent overexpression of 3beta-hydroxysterol Delta24-reductase.
J. Biol. Chem. 284:36442-36452(2009)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D637
Anatomy/cell type resources BTO; BTO_0005181
Encyclopedic resources Wikidata; Q54951522
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number17