Cellosaurus cell line TTE1 (CVCL

Cellosaurus TTE1 (CVCL_D629)

Cross-references
Cell line name	TTE1
Synonyms	TTE-1; TTE 1
Accession	CVCL_D629
Resource Identification Initiative	To cite this cell line use: TTE1 (RRID:CVCL_D629)
Comments	Characteristics: Proliferates at the permissive temperature (33 Celsius). Growth is signicantly prevented at the nonpermissive temperature (39 Celsius) (PubMed=11789682). Doubling time: 24 hours (PubMed=11789682). Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58). Derived from site: In situ; Testis; UBERON=UBERON_0000473. Cell type: Leydig cell; CL=CL_0000178.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6 SV40-tsA58 transgenic.
Sex of cell	Male
Age at sampling	2M
Category	Conditionally immortalized cell line
Publications	PubMed=11789682; DOI=10.1080/014850102753385206 Shoichiro Ohta, Yoshiaki Tabuchi, Nobuaki Yanai, Shinji Asano, Hideki Fuse, Masuo Obinata; Establishment of Leydig cell line, TTE1, from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene. Arch. Androl. 48:43-51(2002) PubMed=15541572; DOI=10.1016/j.mce.2003.05.001 Nafis A. Rahman, Ilpo Tapani Huhtaniemi; Testicular cell lines. Mol. Cell. Endocrinol. 228:53-65(2004) PubMed=17233813; DOI=10.1111/j.1349-7006.2007.00399.x; PMCID=PMC11159456 Masuo Obinata; The immortalized cell lines with differentiation potentials: their establishment and possible application. Cancer Sci. 98:275-283(2007)
Anatomy/cell type resources	BTO; BTO_0005187
Encyclopedic resources	Wikidata; Q54973287
Entry history
Entry creation	22-Oct-2012
Last entry update	14-Aug-2025
Version number	15