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Cellosaurus Panc02 (CVCL_D627)

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Cell line name Panc02
Synonyms Panc-02; Panc 02; Pan02; Pan-02; PAN 02; Panc02-H0
Accession CVCL_D627
Resource Identification Initiative To cite this cell line use: Panc02 (RRID:CVCL_D627)
Comments Doubling time: 61 hours (PubMed=24278292).
Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Disease Mouse pancreatic ductal adenocarcinoma (NCIt: C34041)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_E3IB (HyCyte Panc02-Luc)CVCL_E3IC (HyCyte Panc02-Luc-GFP)CVCL_D7FV (Pan-02-Luc)
CVCL_D628 (Panc02-H7)CVCL_A8QL (Panc02-luc)CVCL_E7SN (Panc02-MUC1)
CVCL_E7SP (Panc02-Neo)CVCL_E1AG (Ubigene Panc02 Bhlhe40 KO)CVCL_E1AH (Ubigene Panc02 Cd44 KO)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Ubigene=YC-C067

Markers:
Mouse STR 4-220.3
Mouse STR 5-516,18
Mouse STR 6-418
Mouse STR 6-717
Mouse STR 12-117
Mouse STR 15-322.3
Mouse STR 18-315
Mouse STR X-129

Run an STR similarity search on this cell line
Publications

PubMed=6692374
Thomas H. Corbett, Billy J. Roberts, Wilbur R. Leopold, John C. Peckham, Lee J. Wilkoff, Daniel Pratt Griswold Jr., Frank M. Schabel Jr.;
Induction and chemotherapeutic response of two transplantable ductal adenocarcinomas of the pancreas in C57BL/6 mice.
Cancer Res. 44:717-726(1984)

PubMed=11558631; DOI=10.1385/IJGC:29:1:37
Bai-Liang Wang, Qian Shi, James Lewis Abbruzzese, Qing-Hua Xiong, Xiang-Dong Le, Ke-Ping Xie;
A novel, clinically relevant animal model of metastatic pancreatic adenocarcinoma biology and therapy.
Int. J. Pancreatol. 29:37-46(2001)

PubMed=20805420; DOI=10.4049/jimmunol.0902609; PMCID=PMC3693576
Jennifer Lynn Gnerlich, Jonathan Bower Mitchem, Joshua S. Weir, Narendra V. Sankpal, Hiroyuki Kashiwagi, Brian A. Belt, Matthew Ryan Porembka, John M. Herndon, Timothy J. Eberlein, Simon Peter Goedegebuure, David C. Linehan;
Induction of Th17 cells in the tumor microenvironment improves survival in a murine model of pancreatic cancer.
J. Immunol. 185:4063-4071(2010)

PubMed=21720167; DOI=10.1159/000329413
Lars Ivo Partecke, Matthias Sendler, Andre Kaeding, Frank Urlich Weiss, Julia V. Mayerle, Annegret Dummer, Trung Dung Nguyen, Nele Albers, Sven Speerforck, Markus M. Lerch, Claus-Dieter Heidecke ...Show all 13 authors... , Wolfram von Bernstorff, Albrecht Stier; Show fewer authors
A syngeneic orthotopic murine model of pancreatic adenocarcinoma in the C57/BL6 mouse using the Panc02 and 6606PDA cell lines.
Eur. Surg. Res. 47:98-107(2011)

PubMed=22208613; DOI=10.2174/156652412799218868; PMCID=PMC3799885
Yi Wang, Yu-Qing Zhang, Jing-Xuan Yang, Xiao-Ling Ni, Shi-He Liu, Zhao-Shen Li, Sally E. Hodges, William E. Fisher, Francis Charles Brunicardi, Richard Alexander Gibbs, Marie-Claude Gingras, Min Li;
Genomic sequencing of key genes in mouse pancreatic cancer cells.
Curr. Mol. Med. 12:331-341(2012)

PubMed=24278292; DOI=10.1371/journal.pone.0080580; PMCID=PMC3835415
Maria P. Torres, Satyanarayana Rachagani, Joshua J. Souchek, Kavita Mallya, Sonny L. Johansson, Surinder Kumar Batra;
Novel pancreatic cancer cell lines derived from genetically engineered mouse models of spontaneous pancreatic adenocarcinoma: applications in diagnosis and therapy.
PLoS ONE 8:e80580.1-e80580.12(2013)

Cross-references
Cell line collections (Providers) CLS; 300501
NCI-DTP; PAN 02
Ubigene; YC-C067
Cell line databases/resources CCRID; 1101MOU-PUMC000446
Anatomy/cell type resources BTO; BTO_0005175
Chemistry resources ChEMBL-Cells; CHEMBL4483161
ChEMBL-Targets; CHEMBL4483283
PubChem_Cell_line; CVCL_D627
Encyclopedic resources Wikidata; Q54937552
Entry history
Entry creation22-Oct-2012
Last entry update27-Nov-2025
Version number18