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Cellosaurus MCF-7 1403 (CVCL_D5YB)

[Text version]
Cell line name MCF-7 1403
Accession CVCL_D5YB
Resource Identification Initiative To cite this cell line use: MCF-7 1403 (RRID:CVCL_D5YB)
Comments Population: Caucasian.
Characteristics: Transfected with a firefly luciferase reporter gene under the control of the clusterin promoter (DOI=10.1016/S0531-5131(03)01154-3).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D5YA (MCF-7:WS8)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

DOI=10.1016/S0531-5131(03)01154-3
Dmitry Klokov, Tracy L. Criswell, Lakshmi Sampath, Konstantin S. Leskov, Kristin Frinkley, Shinako Araki, Meghan Beman, David L. Wilson, David A. Boothman;
Clusterin: a protein with multiple functions as a potential ionizing radiation exposure marker.
Int. Congr. Ser. 1258:219-232(2003)

Cross-references
Encyclopedic resources Wikidata; Q127382747
Entry history
Entry creation02-May-2024
Last entry update14-Aug-2025
Version number4