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Cellosaurus LT97-3 (CVCL_D5XW)

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Cell line name LT97-3
Accession CVCL_D5XW
Resource Identification Initiative To cite this cell line use: LT97-3 (RRID:CVCL_D5XW)
Comments Characteristics: Are 90-100% CD44+ (DOI=10.25365/thesis.6275).
Doubling time: 48-72 hours (DOI=10.25365/thesis.6275).
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Gene deletion; HGNC; HGNC:583; APC; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu257Arg (c.770T>G); ClinVar=VCV000142134; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.1100+30A>T; ClinVar=VCV000810938; Zygosity=Heterozygous (from parent cell line).
Disease Colorectal adenoma (NCIt: C5673)
Familial adenomatous polyposis (NCIt: C3339)
Familial adenomatous polyposis (ORDO: Orphanet_733)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D5XV (LT97-2)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

DOI=10.25365/thesis.6275
Inga Koneczny;
Investigating a model cell line for tumour stem cells in colorectal cancer.
Thesis MSc (2009); University of Vienna; Vienna; Austria

Cross-references
Encyclopedic resources Wikidata; Q127382708
Entry history
Entry creation02-May-2024
Last entry update19-Dec-2024
Version number3