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Cellosaurus TMD12 (CVCL_D5KS)

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Cell line name TMD12
Synonyms Tokyo Medical and Dental university 12
Accession CVCL_D5KS
Resource Identification Initiative To cite this cell line use: TMD12 (RRID:CVCL_D5KS)
Comments Population: Japanese.
Doubling time: ~24 hours (PubMed=36191884).
Omics: Genomics; Whole exome sequencing.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:1699; CD79B; Simple; p.Tyr196Asn (c.586T>A); Zygosity=Heterozygous (PubMed=36191884).
  • Mutation; HGNC; HGNC:7562; MYD88; Simple; p.Leu252Pro (c.755T>C) (p.Leu265Pro, c.794T>C) (L265P); ClinVar= VCV000037055; Zygosity=Heterozygous (PubMed=36191884).
  • Mutation; HGNC; HGNC:8986; PIM1; Simple; c.880+1G>A; Zygosity=Heterozygous; Note=Splice donor mutation (PubMed=36191884).
  • Mutation; HGNC; HGNC:12825; XPO1; Simple; p.Glu571Lys (c.1711G>A); ClinVar=VCV000376695; Zygosity=Heterozygous (PubMed=36191884).
Disease Diffuse large B-cell lymphoma activated B-cell type (NCIt: C36081)
Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 68Y
Category Cancer cell line
Publications

PubMed=36191884; DOI=10.1016/j.exphem.2022.09.005
Toshikage Nagao, Kota Yoshifuji, Daichi Sadato, Yotaro Motomura, Makiko Saito, Kurara Yamamoto, Kouhei Yamamoto, Ayako Nogami;
Establishment and characterization of a new activated B-cell-like DLBCL cell line, TMD12.
Exp. Hematol. 116:37-49(2022)

Cross-references
Encyclopedic resources Wikidata; Q127384397
Entry history
Entry creation02-May-2024
Last entry update14-Aug-2025
Version number5