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Cellosaurus (CVCL_D5IS)

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Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Indonesian.
Characteristics: Produces high level of vasopressin.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gly36Arg (c.106G>A); ClinVar=VCV001334551; Zygosity=Heterozygous (Cosmic-CLP=753589; DepMap=ACH-002077).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val157Profs*9 (c.468_480delCGTCCGCGCCATG); Zygosity=Heterozygous (Cosmic-CLP=753589; DepMap=ACH-002077).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.53
East Asian, North28.73
East Asian, South70.74
South Asian0
European, North0
European, South0
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_D5J0 (MDCK-5KO-EKARrEV-NLS-loxP-NRG1-CreERT2)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP=753589; RCB=RCB1184

Markers:
AmelogeninX,Y
CSF1PO10,12
D13S31710
D16S5399,11
D5S8189,13
D7S82012
TH019
TPOX8,9
vWA16

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Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number40