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Cellosaurus MDCK-dEGF/HBEGF/TGFalpha/EREG KO 2 (CVCL_D5I4)

[Text version]
Cell line name MDCK-dEGF/HBEGF/TGFalpha/EREG KO 2
Synonyms MDCK-QKO
Accession CVCL_D5I4
Resource Identification Initiative To cite this cell line use: MDCK-dEGF/HBEGF/TGFalpha/EREG KO 2 (RRID:CVCL_D5I4)
Comments Knockout cell: Method=CRISPR/Cas9; VGNC; VGNC:40235; EGF.
Knockout cell: Method=CRISPR/Cas9; VGNC; VGNC:111490; EREG.
Knockout cell: Method=CRISPR/Cas9; VGNC; VGNC:41609; HBEGF.
Knockout cell: Method=CRISPR/Cas9; VGNC; VGNC:112755; TGFA.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel; VBO=VBO_0200372.
Hierarchy Parent: CVCL_D5I3 (MDCK-dEGF/HBEGF/TGFalpha KO)
Children:
CVCL_D5IX (MDCK-QKO-EKARrEV-NLS)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=34667080; DOI=10.26508/lsa.202101206; PMCID=PMC8548211
Shu-Hao Lin, Daiki Hirayama, Gembu Maryu, Kimiya Matsuda, Naoya Hino, Eriko Deguchi, Kazuhiro Aoki, Ryo Iwamoto, Kenta Terai, Michiyuki Matsuda;
Redundant roles of EGFR ligands in the ERK activation waves during collective cell migration.
Life Sci. Alliance 5:e202101206.1-e202101206.13(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB1970
Encyclopedic resources Wikidata; Q127382774
Entry history
Entry creation02-May-2024
Last entry update19-Dec-2024
Version number3