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Cellosaurus iCS-05 (CVCL_D5HM)

[Text version]
Cell line name iCS-05
Synonyms iCS05; induced ChondroSarcoma-05
Accession CVCL_D5HM
Resource Identification Initiative To cite this cell line use: iCS-05 (RRID:CVCL_D5HM)
Comments Characteristics: Chorion cells were converted into chondrocytes using BCL6, MITF, MYC, SMARCD3 and T. The cell underwent malignant transformation into chondrosarcoma (PubMed=22833560).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Amnion; UBERON=UBERON_0000305.
Cell type: Chondrocyte; CL=CL_0000138.
Disease Chondrosarcoma (NCIt: C2946)
Chondrosarcoma (ORDO: Orphanet_55880)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling <1D
Category Cancer cell line
STR profile Source(s): PubMed=22833560

Markers:
AmelogeninX,Y
CSF1PO11,12
D3S135815,16
D5S81810
D7S8208,12
D8S117910,13
D13S31712
D16S5399,12
D18S5114,19
D21S1130,31.2
FGA19,22
Penta D12
Penta E15,21
TH016,9.3
TPOX11
vWA14,16

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Publications

PubMed=22833560; DOI=10.1091/mbc.E11-10-0869; PMCID=PMC3442400
Ishii R., Kami D., Toyoda M., Makino H., Gojo S., Ishii T., Umezawa A.
Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors.
Mol. Biol. Cell 23:3511-3521(2012)

Cross-references
Encyclopedic resources Wikidata; Q127382320
Gene expression databases GEO; GSM737454
Entry history
Entry creation02-May-2024
Last entry update10-Apr-2025
Version number3