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Cellosaurus iCS-01 (CVCL_D5HJ)

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Cell line name iCS-01
Synonyms iCS01; induced ChondroSarcoma-01
Accession CVCL_D5HJ
Resource Identification Initiative To cite this cell line use: iCS-01 (RRID:CVCL_D5HJ)
Comments Characteristics: Decidual cells were converted into chondrocytes using BCL6, MITF, MYC, SMARCD3 and T. The cell underwent malignant transformation into chondrosarcoma (PubMed=22833560).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Placenta; UBERON=UBERON_0001987.
Cell type: Chondrocyte; CL=CL_0000138.
Disease Chondrosarcoma (NCIt: C2946)
Chondrosarcoma (ORDO: Orphanet_55880)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_D5HK ! iCS-02
CVCL_D5HL ! iCS-03
Sex of cell Female
Age at sampling Adult
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1553; PubMed=22833560

Markers:
AmelogeninX
CSF1PO11,12
D3S135815
D5S81810,11
D7S8208,11
D8S117910,13
D13S31711
D16S53912,13
D18S5114
D21S1130,31.2
FGA22,26
Penta D10,12
Penta E14,21
TH016
TPOX8,11
vWA16

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Publications

PubMed=22833560; DOI=10.1091/mbc.E11-10-0869; PMCID=PMC3442400
Ryuga Ishii, Daisuke Kami, Masashi Toyoda, Hatsune Makino, Satoshi Gojo, Toshiharu Ishii, Akihiro Umezawa;
Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors.
Mol. Biol. Cell 23:3511-3521(2012)

Cross-references
Cell line collections (Providers) JCRB; JCRB1553
Encyclopedic resources Wikidata; Q127382317
Gene expression databases GEO; GSM737450
Entry history
Entry creation02-May-2024
Last entry update10-Apr-2025
Version number3