Cellosaurus cell line Vk31080.VITRO (CVCL

Cellosaurus Vk31080.VITRO (CVCL_D5FW)

Cross-references
Cell line name	Vk31080.VITRO
Accession	CVCL_D5FW
Resource Identification Initiative	To cite this cell line use: Vk31080.VITRO (RRID:CVCL_D5FW)
Comments	Characteristics: Produces IgA kappa (PubMed=37546905). Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:1352467; Esr1 (Note=Ligand binding domain; with p.Gly525Arg. Fused to Cre = CreERT2). Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P06956; Escherichia phage P1 cre (Note=Fused to ligand domain of mouse Esr1 = CreERT2). Omics: Genomics; Whole genome sequencing. Omics: Transcriptomics; RNAseq. Cell type: Plasma cell; CL=CL_0000786.
Disease	Mouse multiple myeloma (NCIt: C125417)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6 Vk*MYCDLoxP,MDL11 x R26-CreERT2.
Sex of cell	Female
Age at sampling	74W
Category	Cancer cell line
Publications	PubMed=37546905; DOI=10.1101/2023.07.25.550482; PMCID=PMC10402028 Francesco Maura, David G. Coffey, Caleb K. Stein, Esteban Braggio, Bachisio Ziccheddu, Meaghen E. Sharik, Megan Du, Yuliza Tafoya Alvarado, Chang-Xin Shi, Yuan-Xiao Zhu, Erin W. Meermeier ...Show all 15 authors... , Gareth John Morgan, Ola Landgren, Peter Leif Bergsagel, Marta Chesi; Show fewer authors The Vk*MYC mouse model recapitulates human multiple myeloma evolution and genomic diversity. bioRxiv 2023:07.25.550482-07.25.550482(2023)
Encyclopedic resources	Wikidata; Q127384645
Gene expression databases	GEO; GSM8067013 GEO; GSM8077901
Entry history
Entry creation	02-May-2024
Last entry update	14-Aug-2025
Version number	4