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Cellosaurus Vk31080.VITRO (CVCL_D5FW)

[Text version]
Cell line name Vk31080.VITRO
Accession CVCL_D5FW
Resource Identification Initiative To cite this cell line use: Vk31080.VITRO (RRID:CVCL_D5FW)
Comments Characteristics: Produces IgA kappa (PubMed=37546905).
Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:1352467; Esr1 (Note=Ligand binding domain; with p.Gly525Arg. Fused to Cre = CreERT2).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P06956; Escherichia phage P1 cre (Note=Fused to ligand domain of mouse Esr1 = CreERT2).
Omics: Genomics; Whole genome sequencing.
Omics: Transcriptomics; RNAseq.
Disease Mouse multiple myeloma (NCIt: C125417)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 Vk*MYCDLoxP,MDL11 x R26-CreERT2.
Sex of cell Female
Age at sampling 74W
Category Cancer cell line
Publications

PubMed=37546905; DOI=10.1101/2023.07.25.550482; PMCID=PMC10402028
Maura F., Coffey D.G., Stein C.K., Braggio E., Ziccheddu B., Sharik M.E., Du M., Tafoya Alvarado Y., Shi C.-X., Zhu Y.-X., Meermeier E.W., Morgan G.J., Landgren O., Bergsagel P.L., Chesi M.
The Vk*MYC mouse model recapitulates human multiple myeloma evolution and genomic diversity.
bioRxiv 2023:07.25.550482-07.25.550482(2023)

Cross-references
Encyclopedic resources Wikidata; Q127384645
Gene expression databases GEO; GSM8067013
GEO; GSM8077901
Entry history
Entry creation02-May-2024
Last entry update10-Apr-2025
Version number3