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Cellosaurus MLE-15 (CVCL_D581)

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Cell line name MLE-15
Synonyms MLE 15; MLE15; Murine Lung Epithelial-15
Accession CVCL_D581
Resource Identification Initiative To cite this cell line use: MLE-15 (RRID:CVCL_D581)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: FVB/N-Tg(SFTPC-TAg)5.1Jaw transgenic.
Sex of cell Sex unspecified
Age at sampling 5M
Category Transformed cell line
Publications

PubMed=8248207; DOI=10.1073/pnas.90.23.11029; PMCID=PMC47915
Kathryn A. Wikenheiser-Brokamp, Diane Kohmescher Vorbroker, Ward R. Rice, Jean C. Clark, Cindy J. Bachurski, Herbert Kazuto Oie, Jeffrey A. Whitsett;
Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice.
Proc. Natl. Acad. Sci. U.S.A. 90:11029-11033(1993)

PubMed=19263283; DOI=10.1080/01902140802495870; PMCID=PMC3366342
Christina L. Grek, Danforth A. Newton 3rd, Yonh-Zhi Qiu, Xue-Jun Wen, Demetri D. Spyropoulos, John E. Baatz;
Characterization of alveolar epithelial cells cultured in semipermeable hollow fibers.
Exp. Lung Res. 35:155-174(2009)

Cross-references
Cell line collections (Providers) ABM; T0495 - Discontinued
Anatomy/cell type resources BTO; BTO_0005242
Encyclopedic resources Wikidata; Q54905968
Experimental variables resources EFO; EFO_0022752
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number19