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Cellosaurus AT22IJE-T (CVCL_D566)

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Cell line name AT22IJE-T
Accession CVCL_D566
Resource Identification Initiative To cite this cell line use: AT22IJE-T (RRID:CVCL_D566)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Leu762Valfs*2 (c.2282_2283CT[1]) (c.2284_2285delCT); ClinVar=VCV000141325; Zygosity=Unspecified (PubMed=9244351).
Disease Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_F635 (AT22IJE-T pEBS7)CVCL_XG29 (AT22IJE-T pEBS7-YZ3)CVCL_F636 (AT22IJE-T pEBS7-YZ5)
Sex of cell Female
Age at sampling 5Y
Category Transformed cell line
Publications

PubMed=2539904
Yael Ziv, Nicolaas G.J. Jaspers, Sara Etkin, Tsafi Danieli, Luba Trakhtenbrot, Aliza Amiel, Yehoshua Ravia, Yosef Shiloh;
Cellular and molecular characteristics of an immortalized ataxia-telangiectasia (group AB) cell line.
Cancer Res. 49:2495-2501(1989)

PubMed=9244351; DOI=10.1038/sj.onc.1201319
Yael Ziv, Anat Bar-Shira, Iris Pecker, Pamela Russell, Timothy J. Jorgensen, Ilan Tsarfaty, Yosef Shiloh;
Recombinant ATM protein complements the cellular A-T phenotype.
Oncogene 15:159-167(1997)

PubMed=9357546; DOI=10.1016/S0027-5107(97)00119-x
Carl N. Sprung, Tracy M. Bryan, Roger Robert Reddel, John Patrick Murnane;
Normal telomere maintenance in immortal ataxia telangiectasia cell lines.
Mutat. Res. 379:177-184(1997)

Cross-references
Encyclopedic resources Wikidata; Q54750854
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number14