Cellosaurus logo
expasy logo

Cellosaurus AT22IJE-T (CVCL_D566)

[Text version]
Cell line name AT22IJE-T
Accession CVCL_D566
Resource Identification Initiative To cite this cell line use: AT22IJE-T (RRID:CVCL_D566)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 795; ATM; Simple; p.Leu762Valfs*2 (c.2282_2283CT[1]) (c.2284_2285delCT); ClinVar=VCV000141325; Zygosity=Unspecified (PubMed=9244351).
Disease Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
Sex of cell Female
Age at sampling 5Y
Category Transformed cell line

Ziv Y., Jaspers N.G.J., Etkin S., Danieli T., Trakhtenbrot L., Amiel A., Ravia Y., Shiloh Y.
Cellular and molecular characteristics of an immortalized ataxia-telangiectasia (group AB) cell line.
Cancer Res. 49:2495-2501(1989)

PubMed=9244351; DOI=10.1038/sj.onc.1201319
Ziv Y., Bar-Shira A., Pecker I., Russell P., Jorgensen T.J., Tsarfati I., Shiloh Y.
Recombinant ATM protein complements the cellular A-T phenotype.
Oncogene 15:159-167(1997)

PubMed=9357546; DOI=10.1016/s0027-5107(97)00119-x
Sprung C.N., Bryan T.M., Reddel R.R., Murnane J.P.
Normal telomere maintenance in immortal ataxia telangiectasia cell lines.
Mutat. Res. 379:177-184(1997)

Encyclopedic resources Wikidata; Q54750854
Entry history
Entry creation22-Oct-2012
Last entry update29-Jun-2023
Version number13