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Cellosaurus Mel-RM (CVCL_D548)

[Text version]
Cell line name Mel-RM
Synonyms Mel RM
Accession CVCL_D548
Resource Identification Initiative To cite this cell line use: Mel-RM (RRID:CVCL_D548)
Comments Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; None_reported; -; Zygosity=- (PubMed=15048078).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Heterozygous (PubMed=22383533).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=7520026; DOI=10.1002/ijc.2910580413
Hersey P., Si Z.-Y., Smith M.J., Thomas W.D.
Expression of the co-stimulatory molecule B7 on melanoma cells.
Int. J. Cancer 58:527-532(1994)

PubMed=8980186; DOI=10.1002/(SICI)1097-0215(19961211)68:6<795::AID-IJC18>3.0.CO;2-#
Thomas W.D., Smith M.J., Si Z.-Y., Hersey P.
Expression of the co-stimulatory molecule CD40 on melanoma cells.
Int. J. Cancer 68:795-801(1996)

PubMed=9725211; DOI=10.4049/jimmunol.161.5.2195
Thomas W.D., Hersey P.
TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells.
J. Immunol. 161:2195-2200(1998)

PubMed=10364001
Zhang X.-D., Franco A., Myers K., Gray C., Nguyen T., Hersey P.
Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma.
Cancer Res. 59:2747-2753(1999)

PubMed=15048078; DOI=10.1038/sj.onc.1207563
Pavey S., Johansson P., Packer L., Taylor J., Stark M.S., Pollock P.M., Walker G.J., Boyle G.M., Harper U., Cozzi S.-J., Hansen K., Yudt L., Schmidt C., Hersey P., Ellem K.A.O., O'Rourke M.G.E., Parsons P.G., Meltzer P.S., Ringner M., Hayward N.K.
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Oncogene 23:4060-4067(2004)

PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676
Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V., Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma.
Mol. Cancer Ther. 11:888-897(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D548
Anatomy/cell type resources BTO; BTO:0005715
Encyclopedic resources Wikidata; Q54905129
Experimental variables resources EFO; EFO_0022452
Polymorphism and mutation databases Cosmic; 889010
Entry history
Entry creation22-Oct-2012
Last entry update10-Sep-2024
Version number16