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Cellosaurus LES (CVCL_D524)

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Cell line name LES
Accession CVCL_D524
Resource Identification Initiative To cite this cell line use: LES (RRID:CVCL_D524)
Comments Characteristics: Produces IgG kappa.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Plasma cell; CL=CL_0000786.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=7949178; DOI=10.1182/blood.V84.9.3063.3063
James Hardin, Stewart L. MacLeod, Irina Grigorieva, Rui-Xin Chang, Bart Barlogie, Hui-Qing Xiao, Joshua Epstein;
Interleukin-6 prevents dexamethasone-induced myeloma cell death.
Blood 84:3063-3070(1994)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

Cross-references
Encyclopedic resources Wikidata; Q54902445
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number12