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Cellosaurus NCC-DFSP5-C1 (CVCL_D4ZK)

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Cell line name NCC-DFSP5-C1
Accession CVCL_D4ZK
Resource Identification Initiative To cite this cell line use: NCC-DFSP5-C1 (RRID:CVCL_D4ZK)
Comments Part of: NCC sarcoma cell line panel.
Population: Japanese.
Senescence: It is possible that this cell line is not immortal and has a finite life span (personal communication of Kondo, Tadashi).
Doubling time: 35 hours (PubMed=38372888).
Omics: Phenotyping; Drug screening.
Derived from site: In situ; Back, hypodermis; UBERON=UBERON_0001137+UBERON_0002072.
Sequence variations
  • Gene fusion; HGNC; HGNC:2197; COL1A1 + HGNC; HGNC:8800; PDGFB; Name(s)=COL1A1-PDGFB; Note=COL1A1 exon 43 fused to PDGFB exon 2 (PubMed=38372888).
Disease Dermatofibrosarcoma protuberans (NCIt: C4683)
Dermatofibrosarcoma protuberans (ORDO: Orphanet_31112)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 73Y
Category Cancer cell line
STR profile Source(s): PubMed=38372888

Markers:
AmelogeninX,Y
CSF1PO12
D5S81811,13
D7S82010
D13S3179,12
D16S53912,13
D21S1130,31
TH018
TPOX9,11
vWA17,19

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Publications

PubMed=38372888; DOI=10.1007/s13577-024-01030-9
Takuya Ono, Rei Noguchi, Julia Osaki, Taro Akiyama, Yuki Adachi, Naoki Kojima, Yu Toda, Suguru Fukushima, Yuki Yoshimatsu, Akihiko Yoshida, Akira Kawai, Tadashi Kondo;
Establishment and characterization of NCC-DFSP5-C1: a novel patient-derived dermatofibrosarcoma protuberans cell line.
Hum. Cell 37:854-864(2024)

Cross-references
Encyclopedic resources Wikidata; Q127382928
Entry history
Entry creation02-May-2024
Last entry update10-Apr-2025
Version number4