Cellosaurus cell line CZH1 (CVCL

Cellosaurus CZH1 (CVCL_D4ZB)

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Cell line name

CZH1

Accession

CVCL_D4ZB

Resource Identification Initiative

To cite this cell line use: CZH1 (RRID:CVCL_D4ZB)

Comments

Population: Chinese.
Doubling time: ~20 hours (PubMed=38280070).
Omics: Genomics; Whole exome sequencing.
Donor information: Established from a patient that had an extensive smoking history, averaging 40 cigarettes per day over 40 years (PubMed=38280070).
Derived from site: In situ; Pharynx, hypopharynx; UBERON=UBERON_0001051.

Sequence variations

Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Unspecified (PubMed=38280070).

Disease

Hypopharyngeal squamous cell carcinoma (NCIt: C4043)
Squamous cell carcinoma of the hypopharynx (ORDO: Orphanet_494547)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

69Y

Category

Cancer cell line

STR profile

Source(s): PubMed=38280070

Markers:

Amelogenin	X
CSF1PO	11,12
D2S1338	20
D3S1358	15
D5S818	12
D6S1043	18,19
D7S820	8,11
D8S1179	12,15
D12S391	18
D13S317	8,9
D16S539	10,11
D18S51	15
D19S433	13,15.2
D21S11	29,32.2
FGA	24,26
Penta D	8,13
Penta E	10,11,18
TH01	7,9
TPOX	8
vWA	16,17

Publications

PubMed=38280070; DOI=10.1007/s13577-024-01026-5
Jing-Yu Ma, Xiao-Ke Zhu, Yu Heng, Xu-Ping Ding, Lei Tao, Li-Ming Lu;
Establishment and characterization of a novel hypopharyngeal squamous cell carcinoma cell line CZH1 with genetic abnormalities.
Hum. Cell 37:546-559(2024)

Cross-references

Encyclopedic resources

Wikidata; Q127380733

Entry history

Entry creation

02-May-2024

Last entry update

10-Apr-2025

Version number