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Cellosaurus HEK293T PIEZO1 KO (CVCL_D4Z8)

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Cell line name HEK293T PIEZO1 KO
Synonyms HEK-P1KO; Piezo1 knock-out HEK293T
Accession CVCL_D4Z8
Resource Identification Initiative To cite this cell line use: HEK293T PIEZO1 KO (RRID:CVCL_D4Z8)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:28993; PIEZO1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
STR profile Source(s): ATCC=CRL-3519

Markers:
AmelogeninX
CSF1PO12,13
D5S8188,9
D7S82011
D13S31712,14
D16S5399,13
TH017,9.3
TPOX11
vWA16,19,20

Run an STR similarity search on this cell line
Publications

PubMed=26387913; DOI=10.1038/ncomms9329; PMCID=PMC4578306
Viktor Lukacs, Jayanti Mathur, Rong Mao, Pinar Bayrak-Toydemir, Melinda Procter, Stuart M. Cahalan, Helen J. Kim, Michael Bandell, Nicola Longo, Ronald W. Day, David A. Stevenson ...Show all 13 authors... , Ardem Patapoutian, Bryan L. Krock; Show fewer authors
Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia.
Nat. Commun. 6:8329.1-8329.7(2015)

Cross-references
Cell line collections (Providers) ATCC; CRL-3519
Encyclopedic resources Wikidata; Q127381678
Entry history
Entry creation02-May-2024
Last entry update14-Aug-2025
Version number4