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Cellosaurus MS1 GNAQ Q209L (CVCL_D4Z6)

[Text version]
Cell line name MS1 GNAQ Q209L
Accession CVCL_D4Z6
Resource Identification Initiative To cite this cell line use: MS1 GNAQ Q209L (RRID:CVCL_D4Z6)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:4390; GNAQ (Note=With p.Gln209Leu).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58-3).
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Endothelial cell; CL=CL_0000115.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_6502 (Mile Sven 1)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=35053574; DOI=10.3390/cancers14020413; PMCID=PMC8773683
Maiko Sasaki, Yoonhee Jung, Paula E. North, Justin Elsey, Keith Choate, Michael Andrew Toussaint, Christina Huang, Rakan Radi, Adam Joseph Perricone, Victor G. Corces, Jack Leonard Arbiser;
Introduction of mutant GNAQ into endothelial cells induces a vascular malformation phenotype with therapeutic response to imatinib.
Cancers (Basel) 14:413.1-413.11(2022)

Cross-references
Cell line collections (Providers) ATCC; CRL-3530
Encyclopedic resources Wikidata; Q127382889
Entry history
Entry creation02-May-2024
Last entry update14-Aug-2025
Version number4