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Cellosaurus MS1 GNAQ Q209L (CVCL_D4Z6)

[Text version]
Cell line name MS1 GNAQ Q209L
Accession CVCL_D4Z6
Resource Identification Initiative To cite this cell line use: MS1 GNAQ Q209L (RRID:CVCL_D4Z6)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:4390; GNAQ (Note=With p.Gln209Leu).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58-3).
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Endothelial cell; CL=CL_0000115.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_6502 (Mile Sven 1)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=35053574; DOI=10.3390/cancers14020413; PMCID=PMC8773683
Sasaki M., Jung Y., North P.E., Elsey J., Choate K., Toussaint M.A., Huang C., Radi R., Perricone A.J., Corces V.G., Arbiser J.L.
Introduction of mutant GNAQ into endothelial cells induces a vascular malformation phenotype with therapeutic response to imatinib.
Cancers (Basel) 14:413.1-413.11(2022)

Cross-references
Cell line collections (Providers) ATCC; CRL-3530
Encyclopedic resources Wikidata; Q127382889
Entry history
Entry creation02-May-2024
Last entry update19-Dec-2024
Version number3