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Cellosaurus DT28 (CVCL_D4YK)

[Text version]
Cell line name DT28
Accession CVCL_D4YK
Resource Identification Initiative To cite this cell line use: DT28 (RRID:CVCL_D4YK)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Characteristics: When injected into the mammary fat pad of NOD/SCID mice, forms spontaneous metastasis from the orthotopic site to lymph nodes and lung (PubMed=24567196).
Doubling time: 48 hours (PubMed=24567196).
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Finite cell line

PubMed=24567196; DOI=10.1007/s10549-014-2887-9
Drews-Elger K., Brinkman J.A., Miller P.C., Shah S.H., Harrell J.C., da Silva T.G., Ao Z., Schlater A., Azzam D.J., Diehl K., Thomas D., Slingerland J.M., Perou C.M., Lippman M.E., El-Ashry D.
Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures.
Breast Cancer Res. Treat. 144:503-517(2014)

PubMed=34216317; DOI=10.1007/s10549-021-06299-0
Sharma U., Medina-Saenz K., Miller P.C., Troness B., Spartz A., Sandoval-Leon A.C., Parke D.N., Seagroves T.N., Lippman M.E., El-Ashry D.
Heterotypic clustering of circulating tumor cells and circulating cancer-associated fibroblasts facilitates breast cancer metastasis.
Breast Cancer Res. Treat. 189:63-80(2021)

Entry history
Entry creation02-May-2024
Last entry update02-May-2024
Version number1