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Cellosaurus DT28 (CVCL_D4YK)

[Text version]
Cell line name DT28
Accession CVCL_D4YK
Resource Identification Initiative To cite this cell line use: DT28 (RRID:CVCL_D4YK)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Characteristics: When injected into the mammary fat pad of NOD/SCID mice, forms spontaneous metastasis from the orthotopic site to lymph nodes and lung (PubMed=24567196).
Doubling time: 48 hours (PubMed=24567196).
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Finite cell line
Publications

PubMed=24567196; DOI=10.1007/s10549-014-2887-9
Katherine Drews-Elger, Joeli Ann Brinkman, Philip C. Miller, Sanket H. Shah, J. Chuck Harrell, Thiago G. da Silva, Zheng Ao, Amy Schlater, Diana J. Azzam, Kathleen Diehl, Dafydd Thomas ...Show all 15 authors... , Joyce M. Slingerland, Charles M. Perou, Marc E. Lippman, Dorraya El-Ashry; Show fewer authors
Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures.
Breast Cancer Res. Treat. 144:503-517(2014)

PubMed=34216317; DOI=10.1007/s10549-021-06299-0
Utsav Sharma, Kelsie Medina-Saenz, Philip C. Miller, Benjamin Troness, Angela Spartz, Ana Cristina Sandoval-Leon, Deanna N. Parke, Tiffany N. Seagroves, Marc E. Lippman, Dorraya El-Ashry;
Heterotypic clustering of circulating tumor cells and circulating cancer-associated fibroblasts facilitates breast cancer metastasis.
Breast Cancer Res. Treat. 189:63-80(2021)

Cross-references
Encyclopedic resources Wikidata; Q127380806
Entry history
Entry creation02-May-2024
Last entry update10-Sep-2024
Version number2