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Cellosaurus OCCM-30 (CVCL_D4XK)

[Text version]
Cell line name OCCM-30
Synonyms OCCM.30; OCCM30; OC/CM-30; OsteoCalcin/CeMentoblast-30
Accession CVCL_D4XK
Resource Identification Initiative To cite this cell line use: OCCM-30 (RRID:CVCL_D4XK)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Tooth, periodontal ligament; UBERON=UBERON_0008266.
Cell type: Cementoblast; CL=CL_0000061.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: OC-TAg transgenic.
Hierarchy Children:
CVCL_D4XM (OCCM-30 Bsp KO clone 2)CVCL_D4XL (OCCM-30 shTbr2)
Sex of cell Sex unspecified
Age at sampling 40-42D
Category Transformed cell line
Publications

PubMed=10695940; DOI=10.1902/jop.2000.71.1.63
John A. D'Errico, Janice E. Berry, Hong-Jiao Ouyang, Christopher L. Strayhorn, Jolene J. Windle, Martha J. Somerman;
Employing a transgenic animal model to obtain cementoblasts in vitro.
J. Periodontol. 71:63-72(2000)

PubMed=12814226; DOI=10.1097/00004770-200306000-00007
Troy S. Thomson, Janice E. Berry, Martha J. Somerman, Keith L. Kirkwood;
Cementoblasts maintain expression of osteocalcin in the presence of mineral trioxide aggregate.
J. Endod. 29:407-412(2003)

PubMed=14653387; DOI=10.1902/jop.2003.74.10.1423
Hema L. Viswanathan, Janice E. Berry, Brian Lee Foster, Carolyn W. Gibson, Yong Li, Ashok B. Kulkarni, Malcolm L. Snead, Martha J. Somerman;
Amelogenin: a potential regulator of cementum-associated genes.
J. Periodontol. 74:1423-1431(2003)

PubMed=27180803; DOI=10.1038/srep26046; PMCID=PMC4867644
Hwajung Choi, Yu-Hyun Ahn, Tak-Heun Kim, Cheol-Hyeon Bae, Jeong-Chae Lee, Hyung-Keun You, Eui-Sic Cho;
TGF-beta signaling regulates cementum formation through Osterix expression.
Sci. Rep. 6:26046-26046(2016)

PubMed=28866368; DOI=10.1016/j.bone.2017.08.027; PMCID=PMC5730356
Min Ao, Michael B. Chavez, Emily Yin Chu, Kathryn C. Hemstreet, Y. Yin, Manisha C. Yadav, Jose Luis Millan, Larry W. Fisher, Harvey A. Goldberg, Martha J. Somerman, Brian Lee Foster;
Overlapping functions of bone sialoprotein and pyrophosphate regulators in directing cementogenesis.
Bone 105:134-147(2017)

Cross-references
Encyclopedic resources Wikidata; Q127382989
Entry history
Entry creation02-May-2024
Last entry update14-Aug-2025
Version number3