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Cellosaurus NCC-GCTB8-C1 (CVCL_D4C0)

[Text version]
Cell line name NCC-GCTB8-C1
Accession CVCL_D4C0
Resource Identification Initiative To cite this cell line use: NCC-GCTB8-C1 (RRID:CVCL_D4C0)
Comments Part of: NCC sarcoma cell line panel.
Population: Japanese.
Senescence: It is possible that this cell line is not immortal and has a finite life span (personal communication of Kondo, Tadashi).
Doubling time: 26 hours (PubMed=38466561).
Omics: Phenotyping; Drug screening.
Derived from site: In situ; Bone, right proximal tibia; UBERON=UBERON_0008772.
Sequence variations
  • Mutation; HGNC; HGNC:4764; H3-3A; Simple; p.Gly35Trp (c.103G>T) (G34W); Zygosity=Heterozygous (PubMed=38466561).
Disease Malignancy in giant cell tumor of bone (NCIt: C4304)
Giant cell tumor of bone (ORDO: Orphanet_363976)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 32Y
Category Cancer cell line
STR profile Source(s): PubMed=38466561

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81812
D7S82011
D13S31711,12
D16S5399,10
D21S1131,32.2
TH018,9
TPOX8,11
vWA14,17

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Publications

PubMed=38466561; DOI=10.1007/s13577-024-01042-5
Yuki Adachi, Rei Noguchi, Yuki Yoshimatsu, Yooksil Sin, Julia Osaki, Takuya Ono, Shuhei Iwata, Taro Akiyama, Ryuto Tsuchiya, Yu Toda, Shin Ishihara ...Show all 18 authors... , Koichi Ogura, Eisuke Kobayashi, Naoki Kojima, Akihiko Yoshida, Hideki Yokoo, Akira Kawai, Tadashi Kondo; Show fewer authors
Establishment and characterization of two novel patient-derived cell lines from giant cell tumor of bone: NCC-GCTB8-C1 and NCC-GCTB9-C1.
Hum. Cell 37:874-885(2024)

Cross-references
Encyclopedic resources Wikidata; Q127382929
Entry history
Entry creation30-Jan-2024
Last entry update10-Apr-2025
Version number4