Cellosaurus cell line mHypoE-42 (CVCL

Cellosaurus mHypoE-42 (CVCL_D443)

Cross-references
Cell line name	mHypoE-42
Synonyms	mHypoE-N42; N42; N-42
Accession	CVCL_D443
Secondary accession	CVCL_0449
Resource Identification Initiative	To cite this cell line use: mHypoE-42 (RRID:CVCL_D443)
Comments	Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Brain, hypothalamus; UBERON=UBERON_0001898.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell	Male
Age at sampling	Embryo
Category	Transformed cell line
Web pages	Provider; Cedarlane; CLU122; https://www.cedarlanelabs.com/Products/Detail/CLU122?lob=AllProducts
Publications	PubMed=19605792; DOI=10.1095/biolreprod.109.077206; PMCID=PMC6366152 M. Bertan Yilmaz, Andrew Wolfe, You-Hong Cheng, Christine Ann Glidewell-Kenney, James Larry Jameson, Serdar E. Bulun; Aromatase promoter I.f is regulated by estrogen receptor alpha (ESR1) in mouse hypothalamic neuronal cell lines. Biol. Reprod. 81:956-965(2009) PubMed=32960947; DOI=10.1210/endocr/bqaa170 Neruja Loganathan, Emma K. McIlwraith, Denise D. Belsham; BPA differentially regulates NPY expression in hypothalamic neurons through a mechanism involving oxidative stress. Endocrinology 161:bqaa170.1-bqaa170.21(2020) PubMed=32575098; DOI=10.1159/000509592 Neruja Loganathan, Emma K. McIlwraith, Denise D. Belsham; Bisphenol A induces Agrp gene expression in hypothalamic neurons through a mechanism involving ATF3. Neuroendocrinology 111:678-695(2021)
Cell line databases/resources	MCCL; MCC:0000346
Encyclopedic resources	Wikidata; Q54905653
Entry history
Entry creation	22-Oct-2012
Last entry update	14-Aug-2025
Version number	17