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Cellosaurus NALM-24 R (CVCL_D3ZC)

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Cell line name NALM-24 R
Accession CVCL_D3ZC
Resource Identification Initiative To cite this cell line use: NALM-24 R (RRID:CVCL_D3ZC)
Comments Population: Japanese.
Selected for resistance to: UniProtKB; P50591; Human TNFSF10/CD253.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
Disease Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C114819)
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3888 (NALM-24)
Sex of cell Female
Age at sampling 42Y
Category Cancer cell line
Publications

PubMed=18599181; DOI=10.1016/j.exphem.2008.04.011
Francis Dida, Yu-Feng Li, Atsushi Iwao, Takao Deguchi, Eiichi Azuma, Yoshihiro Komada;
Resistance to TRAIL-induced apoptosis caused by constitutional phosphorylation of Akt and PTEN in acute lymphoblastic leukemia cells.
Exp. Hematol. 36:1343-1353(2008)

Cross-references
Encyclopedic resources Wikidata; Q127382921
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number4