Cellosaurus logo
expasy logo

Cellosaurus CH-RE1.22 (CVCL_D3X1)

[Text][XML][JSON]
Cell line name CH-RE1.22
Synonyms RE1.22
Accession CVCL_D3X1
Resource Identification Initiative To cite this cell line use: CH-RE1.22 (RRID:CVCL_D3X1)
Comments Selected for resistance to: UniProtKB; P00588; Corynephage beta diphtheria toxin.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Mutation; UniProtKB; P09445; EEF2; Simple; p.Gly717Arg (c.2149G>A); Zygosity=Heterozygous (PubMed=1353910).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_D3VX (CHO-K1c)
Children:
CVCL_D3WG (CH-RE1.22c)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=1353910; DOI=10.1007/BF01233859
Brian Thomas Foley, Joan Marie Moehring, Thomas John Moehring;
A mutation in codon 717 of the CHO-K1 elongation factor 2 gene prevents the first step in the biosynthesis of diphthamide.
Somat. Cell Mol. Genet. 18:227-231(1992)

PubMed=7559470; DOI=10.1074/jbc.270.39.23218
Brian Thomas Foley, Joan Marie Moehring, Thomas John Moehring;
Mutations in the elongation factor 2 gene which confer resistance to diphtheria toxin and Pseudomonas exotoxin A. Genetic and biochemical analyses.
J. Biol. Chem. 270:23218-23225(1995)

Cross-references
Encyclopedic resources Wikidata; Q127380445
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3