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Cellosaurus OS774 (CVCL_D3W0)

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Cell line name OS774
Accession CVCL_D3W0
Resource Identification Initiative To cite this cell line use: OS774 (RRID:CVCL_D3W0)
Comments Characteristics: Established from a patient-derived xenograft established by implantation of the original tumor under the renal capsule of NSG mice (PubMed=37703185).
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
STR profile Source(s): PubMed=37703185

Markers:
AmelogeninX
CSF1PO10,13
D5S8187,12
D7S82010,12
D13S31711
D16S53911
TH018
TPOX8
vWA14,16

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Publications

PubMed=37703185; DOI=10.1158/1078-0432.CCR-23-0873; PMCID=PMC10870121
Courtney R. Schott, Amanda Lynn Koehne, Leanne C. Sayles, Elizabeth P. Young, Cuyler Luck, Katharine Yu, Alex G. Lee, Marcus R. Breese, Stanley G. Leung, Hang Xu, Avanthi Tayi Shah ...Show all 27 authors... , Heng-Yi Liu, Aviv Spillinger, Inge H. Behroozfard, Kieren D. Marini, Phuong T. Dinh, Maria Victoria Pons-Ventura, Emma N. Vanderboon, Florette K. Hazard, Soo-Jin Cho, Raffi S. Avedian, David G. Mohler, Melissa Zimel, Rosanna Wustrack, Christina Curtis, Marina Sirota, Eric Alejandro Sweet-Cordero; Show fewer authors
Osteosarcoma PDX-derived cell line models for preclinical drug evaluation demonstrate metastasis inhibition by dinaciclib through a genome-targeted approach.
Clin. Cancer Res. 30:849-864(2024)

Cross-references
Encyclopedic resources Wikidata; Q127383001
Entry history
Entry creation30-Jan-2024
Last entry update10-Sep-2024
Version number2