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Cellosaurus A549 PIP4P1 KO (CVCL_D3VW)

[Text version]
Cell line name A549 PIP4P1 KO
Synonyms A549 TMEM55B KO
Accession CVCL_D3VW
Resource Identification Initiative To cite this cell line use: A549 PIP4P1 KO (RRID:CVCL_D3VW)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:19299; PIP4P1.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

DOI=10.1101/2023.06.07.544051
Prosenjit Pal, Matthew Taylor, Pui Yiu Lam, Francesca Tonelli, Chloe A. Hecht, Pawel Lis, Raja Sekhar Nirujogi, Toan K. Phung, Emily A. Dickie, Melanie Wightman, Thomas Macartney ...Show all 13 authors... , Suzanne Ruth Pfeffer, Dario Renato Alessi; Show fewer authors
Parkinson's VPS35[D620N] mutation induces LRRK2 mediated lysosomal association of RILPL1 and TMEM55B.
bioRxiv 2023:06.07.544051-06.07.544051(2023)

Cross-references
Encyclopedic resources Wikidata; Q127378819
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3