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Cellosaurus PC-3 9-7-11 (CVCL_D3N6)

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Cell line name PC-3 9-7-11
Synonyms PSMA/PC-3; Clone 9-7-11
Accession CVCL_D3N6
Resource Identification Initiative To cite this cell line use: PC-3 9-7-11 (RRID:CVCL_D3N6)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3788; FOLH1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=24403448
Yoshiyuki Sugimoto, Maiko Hirota, Kazuhiro Yoshikawa, Makoto Sumitomo, Kogenta Nakamura, Ryuzo Ueda, Rinpei Niwa, Toshiyuki Suzawa, Motoo Yamasaki, Kenya Shitara, Takashi Kato, Kazuyasu Nakamura;
The therapeutic potential of a novel PSMA antibody and its IL-2 conjugate in prostate cancer.
Anticancer Res. 34:89-97(2014)

Cross-references
Encyclopedic resources Wikidata; Q127383017
Entry history
Entry creation30-Jan-2024
Last entry update14-Aug-2025
Version number4