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Cellosaurus iMPEC-3 (CVCL_D3JR)

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Cell line name iMPEC-3
Synonyms immortal Mouse Prostate Epithelial Cell line-3
Accession CVCL_D3JR
Resource Identification Initiative To cite this cell line use: iMPEC-3 (RRID:CVCL_D3JR)
Comments Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03255; Human adenovirus C serotype 5 E1A protein.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5 (Note=E1A).
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Sex of cell Male
Age at sampling 6W
Category Transformed cell line
Publications

PubMed=18603117; DOI=10.1016/S0076-6879(08)01605-4
Robin Mathew, Kurt Degenhardt, Liti Haramaty, Cristina M. Karp, Eileen White;
Immortalized mouse epithelial cell models to study the role of apoptosis in cancer.
Methods Enzymol. 446:77-106(2008)

PubMed=19737977; DOI=10.1158/1541-7786.MCR-09-0166; PMCID=PMC2855683
Kevin Bray, Hsin-Yi Chen, Cristina M. Karp, Michael May, Shridar Ganesan, Vassiliki Karantza-Wadsworth, Robert S. DiPaola, Eileen White;
Bcl-2 modulation to activate apoptosis in prostate cancer.
Mol. Cancer Res. 7:1487-1496(2009)

Cross-references
Encyclopedic resources Wikidata; Q127382373
Entry history
Entry creation30-Jan-2024
Last entry update14-Aug-2025
Version number3