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Cellosaurus iBMK W2.3.1-5RED-6 (CVCL_D3JE)

[Text version]
Cell line name iBMK W2.3.1-5RED-6
Synonyms W2.3.1-5RED-6
Accession CVCL_D3JE
Resource Identification Initiative To cite this cell line use: iBMK W2.3.1-5RED-6 (RRID:CVCL_D3JE)
Comments Knockout cell: Method=KO mouse; MGI; MGI:99702; Bax (Note=1 of 2 alleles).
Genetic integration: Method=Transfection; Gene=FPbase; TXLFX; DsRed2 (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
Genetic integration: Method=Transfection; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03255; Human adenovirus C serotype 5 E1A protein.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5 (Note=E1A).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_D3GT (iBMK W2.3.1-5)
Sex of cell Sex unspecified
Age at sampling 5D
Category Transformed cell line
Publications

PubMed=15314031; DOI=10.1101/gad.1204904; PMCID=PMC515288
Deirdre A. Nelson, Ting-Ting Tan, Arnold B. Rabson, Diana Anderson, Kurt Degenhardt, Eileen White;
Hypoxia and defective apoptosis drive genomic instability and tumorigenesis.
Genes Dev. 18:2095-2107(2004)

PubMed=18603117; DOI=10.1016/S0076-6879(08)01605-4
Robin Mathew, Kurt Degenhardt, Liti Haramaty, Cristina M. Karp, Eileen White;
Immortalized mouse epithelial cell models to study the role of apoptosis in cancer.
Methods Enzymol. 446:77-106(2008)

Cross-references
Encyclopedic resources Wikidata; Q127382245
Entry history
Entry creation30-Jan-2024
Last entry update14-Aug-2025
Version number4