Cellosaurus cell line iBMK Atg5+/+ 6.1B5 (CVCL

Cellosaurus iBMK Atg5+/+ 6.1B5 (CVCL_D3IK)

Cross-references
Cell line name	iBMK Atg5+/+ 6.1B5
Synonyms	6.1B5
Accession	CVCL_D3IK
Resource Identification Initiative	To cite this cell line use: iBMK Atg5+/+ 6.1B5 (RRID:CVCL_D3IK)
Comments	Genetic integration: Method=Transfection; Gene=HGNC; HGNC:990; BCL2. Genetic integration: Method=Transfection; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD). Genetic integration: Method=Transfection; Gene=UniProtKB; P03255; Human adenovirus C serotype 5 E1A protein. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5 (Note=E1A). Derived from site: In situ; Kidney; UBERON=UBERON_0002113. Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6.
Hierarchy	Parent: CVCL_D3I5 (iBMK Atg5+/+ 6.1)
Sex of cell	Sex unspecified
Age at sampling	<2D
Category	Transformed cell line
Publications	PubMed=17510285; DOI=10.1101/gad.1545107; PMCID=PMC1877749 Robin Mathew, Sameera Kongara, Brian Beaudoin, Cristina M. Karp, Kevin Bray, Kurt Degenhardt, Guang-Hua Chen, Sheng-Kan Jin, Eileen White; Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev. 21:1367-1381(2007) PubMed=18603117; DOI=10.1016/S0076-6879(08)01605-4 Robin Mathew, Kurt Degenhardt, Liti Haramaty, Cristina M. Karp, Eileen White; Immortalized mouse epithelial cell models to study the role of apoptosis in cancer. Methods Enzymol. 446:77-106(2008)
Encyclopedic resources	Wikidata; Q127382091
Entry history
Entry creation	30-Jan-2024
Last entry update	14-Aug-2025
Version number	5