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Cellosaurus (CVCL_D3IE)

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Comments Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Heterozygous; Note=In promoter (PubMed=23833040; PubMed=30737244).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro152Leu (c.455C>T); ClinVar=VCV000142766; Zygosity=Homozygous (PubMed=1516062; PubMed=30737244; Cosmic-CLP=924151; DepMap=ACH-001350).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.77
Native American0.3
East Asian, North74.17
East Asian, South22.11
South Asian0.65
European, North0.12
European, South1.88
Disease Thyroid gland anaplastic carcinoma (NCIt: C3878)
Anaplastic thyroid carcinoma (ORDO: Orphanet_142)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_D3IY (iBMK Atg5-/- 7.2/pcDNA3 Cl.1-4)CVCL_D3IZ (iBMK Atg5-/- 7.2B2)CVCL_D3J0 (iBMK Atg5-/- 7.2B3)
CVCL_D3J1 (iBMK Atg5-/- 7.2B6)CVCL_D3J2 (iBMK Atg5-/- 7.2B9)
Sex of cell Female
Age at sampling 44Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP=924151; DSMZ=ACC-580; JCRB=JCRB0164; PubMed=25877200; PubMed=30737244; RCB=RCB0452

Markers:

Run an STR similarity search on this cell line
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number44