Cellosaurus logo
expasy logo

Cellosaurus iBMK D3 (CVCL_D3FV)

[Text][XML][JSON]
Cell line name iBMK D3
Synonyms D3; immortalized Baby Mouse Kidney epithelial cell line D3
Accession CVCL_D3FV
Resource Identification Initiative To cite this cell line use: iBMK D3 (RRID:CVCL_D3FV)
Comments Knockout cell: Method=KO mouse; MGI; MGI:1097161; Bak1.
Knockout cell: Method=KO mouse; MGI; MGI:99702; Bax.
Genetic integration: Method=Transfection; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03255; Human adenovirus C serotype 5 E1A protein.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5 (Note=E1A).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_D3JL (iBMK D3.19K-4)CVCL_D3JM (iBMK D3.19K-7)CVCL_D3JN (iBMK D3.19K-8)
CVCL_D3GB (iBMK D3.Akt-D5)CVCL_D3GC (iBMK D3.Akt-F7)CVCL_D3GD (iBMK D3.Akt-G1)
CVCL_D3G9 (iBMK D3.B4)CVCL_D3GF (iBMK D3.Bcl2-3)CVCL_D3GG (iBMK D3.Bcl2-4)
CVCL_D3GH (iBMK D3.Bcl2-6)CVCL_D3GA (iBMK D3.C4)CVCL_D3GE (iBMK D3 EGFP-LC3)
CVCL_D3GI (iBMK D3.Hras-1)CVCL_D3GJ (iBMK D3.Hras-3)CVCL_D3GK (iBMK D3.Hras-6)
CVCL_D3GL (iBMK D3.Raf-1)CVCL_D3GM (iBMK D3.Raf-2)CVCL_D3GN (iBMK D3.Raf-3)
CVCL_D3GP (iBMK D3.zeo-1)CVCL_D3GQ (iBMK D3.zeo-2)CVCL_D3GR (iBMK D3.zeo-3)
Sex of cell Sex unspecified
Age at sampling 5D
Category Transformed cell line
Publications

PubMed=11836241; DOI=10.1074/jbc.M109939200
Kurt Degenhardt, Ramya Sundararajan, Tullia Lindsten, Craig B. Thompson, Eileen White;
Bax and Bak independently promote cytochrome C release from mitochondria.
J. Biol. Chem. 277:14127-14134(2002)

PubMed=12242152; DOI=10.1016/S1535-6108(02)00126-5
Kurt Degenhardt, Guang-Hua Chen, Tullia Lindsten, Eileen White;
BAX and BAK mediate p53-independent suppression of tumorigenesis.
Cancer Cell 2:193-203(2002)

PubMed=18603117; DOI=10.1016/S0076-6879(08)01605-4
Robin Mathew, Kurt Degenhardt, Liti Haramaty, Cristina M. Karp, Eileen White;
Immortalized mouse epithelial cell models to study the role of apoptosis in cancer.
Methods Enzymol. 446:77-106(2008)

Cross-references
Encyclopedic resources Wikidata; Q127382170
Entry history
Entry creation30-Jan-2024
Last entry update14-Aug-2025
Version number4