Cellosaurus cell line IKARS1 (CVCL

Cross-references
Cell line name	IKARS1
Synonyms	Immortalized Knocked out AR Schwann cells 1
Accession	CVCL_D3FL
Resource Identification Initiative	To cite this cell line use: IKARS1 (RRID:CVCL_D3FL)
Comments	Knockout cell: Method=KO mouse; MGI; MGI:1353494; Akr1b1. Derived from site: In situ; Dorsal root ganglion; UBERON=UBERON_0000044. Cell type: Schwann cell; CL=CL_0002573.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6N B6.Cg-Akr1b1tm1.1Kga.
Sex of cell	Female
Age at sampling	8-12W
Category	Spontaneously immortalized cell line
Publications	PubMed=29238976; DOI=10.1111/jnc.14277 Niimi N., Yako H., Takaku S., Kato H., Matsumoto T., Nishito Y., Watabe K., Ogasawara S., Mizukami H., Yagihashi S., Chung S.K., Sango K. A spontaneously immortalized Schwann cell line from aldose reductase-deficient mice as a useful tool for studying polyol pathway and aldehyde metabolism. J. Neurochem. 144:710-722(2018) PubMed=33494154; DOI=10.3390/ijms22031031; PMCID=PMC7864348 Niimi N., Yako H., Takaku S., Chung S.K., Sango K. Aldose reductase and the polyol pathway in Schwann cells: old and new problems. Int. J. Mol. Sci. 22:1031.1-1031.14(2021)
Cell line collections (Providers)	ABM; T0798
Encyclopedic resources	Wikidata; Q127382345
Entry history
Entry creation	30-Jan-2024
Last entry update	10-Apr-2025
Version number	3