Cellosaurus cell line T1 1Cr NKX2.1 Pt 1 (CVCL

Cellosaurus T1 1Cr NKX2.1 Pt 1 (CVCL_D3C4)

Cross-references
Cell line name	T1 1Cr NKX2.1 Pt 1
Synonyms	T1; T1-1Cr4
Accession	CVCL_D3C4
Resource Identification Initiative	To cite this cell line use: T1 1Cr NKX2.1 Pt 1 (RRID:CVCL_D3C4)
Comments	From: Center for Regenerative Medicine; Boston; USA. Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:11825; NKX2-1; Simple; p.Pro129Glyfs (c.384_391delGCCGTACC); Zygosity=Unspecified (PubMed=26593959).
Disease	Choreoathetosis, hypothyroidism, and neonatal respiratory distress (NCIt: C202546) Brain-lung-thyroid syndrome (ORDO: Orphanet_209905)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	5Y
Category	Induced pluripotent stem cell
Web pages	Provider; CReM; 590; https://stemcellbank.bu.edu/Catalog/Item/Details/590
Publications	PubMed=26593959; DOI=10.1016/j.stem.2015.09.004; PMCID=PMC4666682 Anita Agatha Kurmann, Maria Serra, Finn Hawkins, Scott A. Rankin, Munemasa Mori, Inna Astapova, Soumya Ullas, Sui Lin, Melanie Bilodeau, Janet Rossant, Jyh-Chang Jean ...Show all 17 authors... , Laertis Ikonomou, Robin R. Deterding, John M. Shannon, Aaron M. Zorn, Anthony Neil Hollenberg, Darrell N. Kotton; Show fewer authors Regeneration of thyroid function by transplantation of differentiated pluripotent stem cells. Cell Stem Cell 17:527-542(2015)
Encyclopedic resources	Wikidata; Q127384360
Entry history
Entry creation	30-Jan-2024
Last entry update	10-Apr-2025
Version number	4