Cellosaurus cell line mHypoA-2/12 (CVCL

Cellosaurus mHypoA-2/12 (CVCL_D385)

Cross-references
Cell line name	mHypoA-2/12
Accession	CVCL_D385
Resource Identification Initiative	To cite this cell line use: mHypoA-2/12 (RRID:CVCL_D385)
Comments	Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Brain, hypothalamus; UBERON=UBERON_0001898.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6.
Sex of cell	Male
Age at sampling	2M
Category	Transformed cell line
Web pages	Provider; Cedarlane; CLU177; https://www.cedarlanelabs.com/Products/Detail/CLU177?lob=AllProducts
Publications	PubMed=19703933; DOI=10.1096/fj.09-133454 Belsham D.D., Fick L.J., Dalvi P.S., Centeno M.-L., Chalmers J.A., Lee P.K.P., Wang Y.-Y., Drucker D.J., Koletar M.M. Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons. FASEB J. 23:4256-4265(2009) PubMed=32960947; DOI=10.1210/endocr/bqaa170 Loganathan N., McIlwraith E.K., Belsham D.D. BPA differentially regulates NPY expression in hypothalamic neurons through a mechanism involving oxidative stress. Endocrinology 161:bqaa170.1-bqaa170.21(2020) PubMed=32575098; DOI=10.1159/000509592 Loganathan N., McIlwraith E.K., Belsham D.D. Bisphenol A induces Agrp gene expression in hypothalamic neurons through a mechanism involving ATF3. Neuroendocrinology 111:678-695(2021)
Encyclopedic resources	Wikidata; Q54905578
Entry history
Entry creation	22-Oct-2012
Last entry update	10-Apr-2025
Version number	15