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Cellosaurus NSC-34 (CVCL_D356)

[Text version]
Cell line name NSC-34
Synonyms NSC 34; NSC34; Neuroblastoma x Spinal Cord-34
Accession CVCL_D356
Resource Identification Initiative To cite this cell line use: NSC-34 (RRID:CVCL_D356)
Comments Characteristics: Produced by the fusion of motor neuron enriched, embryonic 12-14 days mouse spinal cord cells with N18TG2 (PubMed=1467557).
Omics: Deep proteome analysis.
Miscellaneous: STR profile from personal communication of Rodriguez-Tarduchy Segovia G.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2132 (N18TG2)
Category Hybrid cell line
STR profile Source(s): Direct_author_submission

Mouse STR 1-111
Mouse STR 1-217,18
Mouse STR 2-19,16
Mouse STR 3-213,14
Mouse STR 4-219.3,22.3
Mouse STR 5-514,15,17
Mouse STR 6-418.3,19,20
Mouse STR 6-712,15
Mouse STR 7-125.2,26.2,30
Mouse STR 8-116,17
Mouse STR 11-215,16
Mouse STR 12-116,17
Mouse STR 13-116.2,17.2,18.2
Mouse STR 15-322.3,23.3
Mouse STR 17-215,16
Mouse STR 18-322,23
Mouse STR 19-212,13
Mouse STR X-125,26,29

Run an STR similarity search on this cell line
Web pages https://www.cedarlanelabs.com/Products/Detail/CLU140?lob=Cellutions

PubMed=1467557; DOI=10.1002/aja.1001940306
Cashman N.R., Durham H.D., Blusztajn J.K., Oda K., Tabira T., Shaw I.T., Dahrouge S., Antel J.P.
Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons.
Dev. Dyn. 194:209-221(1992)

PubMed=17896795; DOI=10.1002/jnr.21507
Matusica D., Fenech M.P., Rogers M.-L., Rush R.A.
Characterization and use of the NSC-34 cell line for study of neurotrophin receptor trafficking.
J. Neurosci. Res. 86:553-565(2008)

PubMed=25193168; DOI=10.1074/mcp.M113.037291
Hornburg D., Drepper C., Butter F., Meissner F., Sendtner M., Mann M.
Deep proteomic evaluation of primary and cell line motoneuron disease models delineates major differences in neuronal characteristics.
Mol. Cell. Proteomics 13:3410-3420(2014)

PubMed=27242431; DOI=10.3389/fncel.2016.00118
Madji Hounoum B., Vourc'h P., Felix R., Corcia P., Patin F., Gueguinou M., Potier-Cartereau M., Vandier C., Raoul C., Andres C.R., Mavel S., Blasco H.
NSC-34 motor neuron-like cells are unsuitable as experimental model for glutamate-mediated excitotoxicity.
Front. Cell. Neurosci. 10:118.1-118.12(2016)

Cell line databases/resources Lonza; 5
Anatomy/cell type resources BTO; BTO:0004488
Encyclopedic resources Wikidata; Q54931057
Entry history
Entry creation22-Oct-2012
Last entry update29-Jun-2023
Version number11