| Cell line name |
NSC-34 |
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| Synonyms |
NSC 34; NSC34; Neuroblastoma x Spinal Cord-34 |
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| Accession |
CVCL_D356 |
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| Resource Identification Initiative |
To cite this cell line use: NSC-34 (RRID:CVCL_D356) |
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| Comments |
Characteristics: Produced by the fusion of motor neuron enriched, embryonic 12-14 days mouse spinal cord cells with N18TG2 (PubMed=1467557).
Omics: Proteomics.
Omics: Proteomics; Quantitative.
Miscellaneous: STR profile from personal communication of Rodriguez-Tarduchy Segovia, Gemma. |
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| Species of origin |
Mus musculus (Mouse)
(NCBI Taxonomy: 10090) |
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| Hierarchy |
Parent: CVCL_2132 (N18TG2)
Children:
|
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| Category |
Hybrid cell line |
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| STR profile |
Source(s): Direct_author_submission
Markers:| Mouse STR 1-1 | 11 |
| Mouse STR 1-2 | 17,18 |
| Mouse STR 2-1 | 9,16 |
| Mouse STR 3-2 | 13,14 |
| Mouse STR 4-2 | 19.3,22.3 |
| Mouse STR 5-5 | 14,15,17 |
| Mouse STR 6-4 | 18.3,19,20 |
| Mouse STR 6-7 | 12,15 |
| Mouse STR 7-1 | 25.2,26.2,30 |
| Mouse STR 8-1 | 16,17 |
| Mouse STR 11-2 | 15,16 |
| Mouse STR 12-1 | 16,17 |
| Mouse STR 13-1 | 16.2,17.2,18.2 |
| Mouse STR 15-3 | 22.3,23.3 |
| Mouse STR 17-2 | 15,16 |
| Mouse STR 18-3 | 22,23 |
| Mouse STR 19-2 | 12,13 |
| Mouse STR X-1 | 25,26,29 |
Run an STR similarity search on this cell line |
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| Web pages |
Info; Wikipedia; -; https://it.wikipedia.org/wiki/NSC-34
Provider; Cedarlane; CLU140; https://www.cedarlanelabs.com/Products/Detail/CLU140?lob=AllProducts |
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| Publications | PubMed=1467557; DOI=10.1002/aja.1001940306
Neil R. Cashman, Heather D. Durham, Jan Krzysztof Blusztajn, Kenichiro Oda, Takeshi Tabira, Ivan T. Shaw, Simone Dahrouge, Jack P. Antel;
Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons.
Dev. Dyn. 194:209-221(1992) PubMed=17896795; DOI=10.1002/jnr.21507
Dusan Matusica, Matthew P. Fenech, Mary-Louise Rogers, Robert A. Rush;
Characterization and use of the NSC-34 cell line for study of neurotrophin receptor trafficking.
J. Neurosci. Res. 86:553-565(2008) PubMed=25193168; DOI=10.1074/mcp.M113.037291; PMCID=PMC4256493
Daniel Hornburg, Carsten Drepper, Falk Butter, Felix Meissner, Michael Sendtner, Matthias Mann;
Deep proteomic evaluation of primary and cell line motoneuron disease models delineates major differences in neuronal characteristics.
Mol. Cell. Proteomics 13:3410-3420(2014) PubMed=27242431; DOI=10.3389/fncel.2016.00118; PMCID=PMC4860417
Blandine Madji Hounoum, Patrick Vourc'h, Romain Felix, Philippe Corcia, Franck Patin, Maxime Gueguinou, Marie Potier-Cartereau, Christophe Vandier, Cedric Raoul, Christian R. Andres, Sylvie Mavel, Helene Blasco;
NSC-34 motor neuron-like cells are unsuitable as experimental model for glutamate-mediated excitotoxicity.
Front. Cell. Neurosci. 10:118.1-118.12(2016) PubMed=28837265; DOI=10.1002/pmic.201700161; PMCID=PMC5828681
Joshua Beri, Tara Elizabeth Nash, Rubia Maysa Martin, Michael Seth Bereman;
Exposure to BMAA mirrors molecular processes linked to neurodegenerative disease.
Proteomics 17:e1700161.1-e1700161.10(2017) |
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| Cross-references |
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| Cell line databases/resources |
Lonza; 5
|
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| Anatomy/cell type resources |
BTO; BTO_0004488
|
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| Encyclopedic resources |
Wikidata; Q54931057
|
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| Proteomic databases |
PRIDE; PXD000666
PRIDE; PXD004913
PRIDE; PXD007178
|
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| Entry history |
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| Entry creation | 22-Oct-2012 |
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| Last entry update | 14-Aug-2025 |
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| Version number | 15 |
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