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Cellosaurus SCC13-MET-KOc4-3 (CVCL_D2XR)

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Cell line name SCC13-MET-KOc4-3
Accession CVCL_D2XR
Resource Identification Initiative To cite this cell line use: SCC13-MET-KOc4-3 (RRID:CVCL_D2XR)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:7029; MET.
Derived from site: In situ; Face, skin; UBERON=UBERON_1000021.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu258Lys (c.772G>A); ClinVar=VCV000012348; Zygosity=Unspecified (from parent cell line).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4029 (SCC-13)
Sex of cell Female
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=34593609; DOI=10.1158/1541-7786.MCR-21-0306; PMCID=PMC10088464
Xi Chen, Gautam Adhikary, Suruchi Shrestha, Wen Xu, Jeffrey W. Keillor, Warren Naselsky, Richard L. Eckert;
Transglutaminase 2 maintains hepatocyte growth factor signaling to enhance the cancer cell phenotype.
Mol. Cancer Res. 19:2026-2035(2021)

Cross-references
Encyclopedic resources Wikidata; Q127384191
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3