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Cellosaurus RERF-LC-A1/hPDPN (CVCL_D2U4)

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Cell line name RERF-LC-A1/hPDPN
Synonyms RERF-LC-AI/hPDPN
Accession CVCL_D2U4
Resource Identification Initiative To cite this cell line use: RERF-LC-A1/hPDPN (RRID:CVCL_D2U4)
Comments Population: Chinese; Taiwan.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:29602; PDPN.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Leu858Arg (c.2573T>G); ClinVar=VCV000016609; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln104Ter (c.310C>T); ClinVar=VCV000566924; Zygosity=Homozygous (from parent cell line).
Disease Lung squamous cell carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4402 (RERF-LC-A1)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=25080943; DOI=10.1038/srep05924; PMCID=PMC4118152
Yukinari Kato, Mika Kato Kaneko;
A cancer-specific monoclonal antibody recognizes the aberrantly glycosylated podoplanin.
Sci. Rep. 4:5924.1-5924.9(2014)

PubMed=28387591; DOI=10.1089/mab.2017.0001
Shinji Yamada, Satoshi Ogasawara, Mika Kato Kaneko, Yukinari Kato;
LpMab-23: a cancer-specific monoclonal antibody against human podoplanin.
Monoclon. Antib. Immunodiagn. Immunother. 36:72-76(2017)

Cross-references
Encyclopedic resources Wikidata; Q127384050
Entry history
Entry creation30-Jan-2024
Last entry update14-Aug-2025
Version number4