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Cellosaurus UM-SCC-92 EGFR KO (CVCL_D2PH)

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Cell line name UM-SCC-92 EGFR KO
Synonyms UM-SCC-92 EGFR K/O
Accession CVCL_D2PH
Resource Identification Initiative To cite this cell line use: UM-SCC-92 EGFR KO (RRID:CVCL_D2PH)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:3236; EGFR (Note=3 of 3 alleles).
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7796 (UM-SCC-92)
Sex of cell Female
Age at sampling 38Y
Category Cancer cell line
Publications

PubMed=37844343; DOI=10.1016/j.archoralbio.2023.105822; PMCID=PMC11209876
Megan L. Ludwig, Nicole L. Michmerhuizen, Jia-Yu Wang, Andrew C. Birkeland, Behirda K. Majchrowski, Sai Vineet Nimmagadda, Jing-Yi Zhai, Apurva Bhangale, Aditi Kulkarni, Hui Jiang, Paul L. Swiecicki, J. Chad Brenner;
Multi-kinase compensation rescues EGFR knockout in a cell line model of head and neck squamous cell carcinoma.
Arch. Oral Biol. 156:105822.1-105822.11(2023)

Cross-references
Encyclopedic resources Wikidata; Q127384574
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3