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Cellosaurus FDCP Mix A4/LRARa403SN c.4 (CVCL_D1L4)

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Cell line name FDCP Mix A4/LRARa403SN c.4
Accession CVCL_D1L4
Resource Identification Initiative To cite this cell line use: FDCP Mix A4/LRARa403SN c.4 (RRID:CVCL_D1L4)
Comments Characteristics: IL3 dependent.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:9864; RARA (Note=RARalpha403; truncated version AA 1-403).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 x DBA/2.
Hierarchy Parent: CVCL_2040 (FDCP-Mix cl.A4)
Category Factor-dependent cell line
Publications

PubMed=1334022; DOI=10.1101/gad.6.12a.2258
Schickwann Tsai, Stephen H. Bartelmez, Richard Heyman, Klaus Damm, Ronald Mark Evans, Steven J. Collins;
A mutated retinoic acid receptor-alpha exhibiting dominant-negative activity alters the lineage development of a multipotent hematopoietic cell line.
Genes Dev. 6:2258-2269(1992)

Patent=US5830760
Schickwann Tsai, Steven J. Collins;
Creating novel hematopoietic cell lines by expressing altered retinoic acid receptors.
Patent number US5830760, 03-Nov-1998

Cross-references
Encyclopedic resources Wikidata; Q127380850
Entry history
Entry creation30-Jan-2024
Last entry update14-Aug-2025
Version number4