Cellosaurus logo
expasy logo

Cellosaurus HEK293T D9 T antigen deletion clone #62 (CVCL_D1HQ)

[Text version]
Cell line name HEK293T D9 T antigen deletion clone #62
Accession CVCL_D1HQ
Resource Identification Initiative To cite this cell line use: HEK293T D9 T antigen deletion clone #62 (RRID:CVCL_D1HQ)
Comments Characteristics: Using CRISPR/Cas9 the SV40 large and small T-antigen coding sequences were deleted (PubMed=32775497).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D1HM (HEK293T D9)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=32775497; DOI=10.1016/j.omtm.2020.07.006; PMCID=PMC7397404
Dahae Hailey Bae, Michael Marino, Brian Iaffaldano, Sydney Fenstermaker, Sandra A. Afione, Takele Argaw, Jacob McCright, Anna Kwilas, John A. Chiorini, Andrew E. Timmons, Jakob Reiser;
Design and testing of vector-producing HEK293T cells bearing a genomic deletion of the SV40 T antigen coding region.
Mol. Ther. Methods Clin. Dev. 18:631-638(2020)

Cross-references
Encyclopedic resources Wikidata; Q127381674
Entry history
Entry creation30-Jan-2024
Last entry update14-Aug-2025
Version number3