• Gene fusion; HGNC; HGNC:13575; BRD4 + HGNC; HGNC:29919; NUTM1; Name(s)=BRD4-NUTM1, BRD4-NUT (PubMed=23604113; PubMed=24736545).
  

PubMed=23604113; DOI=10.1038/onc.2013.126; PMCID=PMC3942361
Adlai Rashad Grayson, Erica M. Walsh, Michael J. Cameron, Jernej Godec, Todd Ashworth, Jessica M. Ambrose, Alexandra B. Aserlind, Hongfang Wang, Gerard Ian Evan, Michael J. Kluk, James E. Bradner ...Show all 13 authors... , Jon Christopher Aster, Christopher Alexander French; Show fewer authors
MYC, a downstream target of BRD-NUT, is necessary and sufficient for the blockade of differentiation in NUT midline carcinoma.
Oncogene 33:1736-1742(2014)

PubMed=24736545; DOI=10.1158/0008-5472.CAN-13-2658; PMCID=PMC4097982
Ran-Ran Wang, Wei Liu, Christine M. Helfer, James E. Bradner, Jason L. Hornick, Susan M. Janicki, Christopher Alexander French, Jian-Xin You;
Activation of SOX2 expression by BRD4-NUT oncogenic fusion drives neoplastic transformation in NUT midline carcinoma.
Cancer Res. 74:3332-3343(2014)

PubMed=30135075; DOI=10.1101/gad.315648.118; PMCID=PMC6120715
Sida Liao, Ophelia Maertens, Karen Marie Cichowski, Stephen Joseph Elledge;
Genetic modifiers of the BRD4-NUT dependency of NUT midline carcinoma uncovers a synergism between BETis and CDK4/6is.
Genes Dev. 32:1188-1200(2018)