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Cellosaurus ImGIST (CVCL_D1GJ)

[Text version]
Cell line name ImGIST
Synonyms Immortalized GastroIntestinal Stromal Tumor cells
Accession CVCL_D1GJ
Resource Identification Initiative To cite this cell line use: ImGIST (RRID:CVCL_D1GJ)
Comments Population: Chinese.
Doubling time: 37.8 hours (PubMed=37686448).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
Cell type: Interstitial cell of Cajal; CL=CL_0002088.
Sequence variations
Disease Gastrointestinal stromal tumor (NCIt: C3868)
Gastrointestinal stromal tumor (ORDO: Orphanet_44890)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 64Y
Category Transformed cell line
STR profile Source(s): PubMed=37686448

Markers:
AmelogeninX
CSF1PO10,11
D1S165611,16
D2S133822,24
D3S135815,17
D5S81810,12
D6S104312
D7S8208,13
D8S117910,11
D12S39119,20
D13S3178
D16S53911,12
D18S5117
D19S43316,17.2
D21S1129,30
FGA23,24
Penta D10,11
Penta E12,20
TH019,10
TPOX8
vWA14

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Publications

PubMed=37686448; DOI=10.3390/ijms241713640; PMCID=PMC10487453
Xiang-Chen Hu, Peng Su, Bo Liu, Jing-Wei Guo, Zi-Tong Wang, Cai He, Zhe Wang, You-Wei Kou;
Characterization of a human gastrointestinal stromal tumor cell line established by SV40LT-mediated immortalization.
Int. J. Mol. Sci. 24:13640.1-13640.15(2023)

Cross-references
Encyclopedic resources Wikidata; Q127382353
Entry history
Entry creation30-Jan-2024
Last entry update14-Aug-2025
Version number5