Cellosaurus cell line SCCOHT-CH-1 (CVCL

Cellosaurus SCCOHT-CH-1 (CVCL_D1GG)

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Cell line name

SCCOHT-CH-1

Accession

CVCL_D1GG

Resource Identification Initiative

To cite this cell line use: SCCOHT-CH-1 (RRID:CVCL_D1GG)

Comments

Population: Chinese.
Characteristics: Has extremely strong migratory and invasive abilities (PubMed=37535222).
Doubling time: 33.02 hours (PubMed=37535222).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.

Sequence variations

Mutation; HGNC; HGNC:11100; SMARCA4; Simple; c.939_940insT; Zygosity=Heterozygous (PubMed=37535222).
Mutation; HGNC; HGNC:11100; SMARCA4; Simple; p.Tyr877Tyr (c.2631C>A); ClinVar=VCV000537876; Zygosity=Heterozygous (PubMed=37535222).

Disease

Ovarian small cell carcinoma, hypercalcemic type (NCIt: C40439)
Small cell carcinoma of the ovary (ORDO: Orphanet_370396)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

38Y

Category

Cancer cell line

STR profile

Source(s): PubMed=37535222

Markers:

Amelogenin	X
CSF1PO	10,11
D2S1338	19,24
D3S1358	14,15
D5S818	7,10
D7S820	9,10
D8S1179	16
D13S317	8
D16S539	9,13
D18S51	13,16
D19S433	11,14.2
D21S11	30,32.2
FGA	24,26
TH01	7,9
TPOX	8
vWA	14,17

Publications

PubMed=37535222; DOI=10.1007/s13577-023-00966-8; PMCID=PMC10587334
Yi Gao, Ke-Wei Zheng, Ming-Yi Kang, Jing Xu, Yan Ning, Wei-Guo Hu, Ke Li, Yu Kang, Cong-Jian Xu;
Establishment and characterization of a novel cell line (SCCOHT-CH-1) and PDX models derived from Chinese patients of small cell ovarian carcinoma of the hypercalcemic type.
Hum. Cell 36:2214-2227(2023)

Cross-references

Encyclopedic resources

Wikidata; Q127384193

Entry history

Entry creation

30-Jan-2024

Last entry update

19-Dec-2024

Version number