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Cellosaurus S2 PfRH5 variant 4 (CVCL_D1FW)

[Text version]
Cell line name S2 PfRH5 variant 4
Synonyms S2 PfRH5 v4.0
Accession CVCL_D1FW
Resource Identification Initiative To cite this cell line use: S2 PfRH5 variant 4 (RRID:CVCL_D1FW)
Comments Group: Insect cell line.
Group: Malaria research cell line.
Transfected with: UniProtKB; Q8IFM5; Plasmodium falciparum (isolate 3D7) reticulocyte-binding protein homolog 5 (RH5) (PfRH5) (with p.Met1_Phe25del, p.Asn38Gln, p.Asn214Gln and a C-terminal His6 tag).
Transfected with: FlyBase_Gene; FBgn0001218; Hsc70-3 (AA 1-18 = Signal sequence).
Transfected with: UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Species of origin Drosophila melanogaster (Fruit fly) (NCBI Taxonomy: 7227)
Breed/subspecies: Oregon-R.
Hierarchy Parent: CVCL_A8PY (HighMan-S2)
Sex of cell Male
Age at sampling Late embryonic stage
Category Spontaneously immortalized cell line

PubMed=27457156; DOI=10.1038/srep30357
Hjerrild K.A., Jin J., Wright K.E., Brown R.E., Marshall J.M., Labbe G.M., Silk S.E., Cherry C.J., Clemmensen S.B., Jorgensen T., Illingworth J.J., Alanine D.G.W., Milne K.H., Ashfield R., de Jongh W.A., Douglas A.D., Higgins M.K., Draper S.J.
Production of full-length soluble Plasmodium falciparum RH5 protein vaccine using a Drosophila melanogaster Schneider 2 stable cell line system.
Sci. Rep. 6:30357-30357(2016)

Entry history
Entry creation30-Jan-2024
Last entry update30-Jan-2024
Version number1